R-3
Metabolic Research Peptide
$70
| Pack size | 1 vial, size selected above |
| Also known as | LY3437943 |
| Compound type | Lipidated peptide; GIP / GLP-1 / glucagon receptor triple agonist |
| Sequence | Y-Aib-QGTFTSDYSI-αMeL-LDK-K(AEEA-γGlu-C20 diacid)-AQ-Aib-AFIEYLLEGGPSSGAPPPS-NH2 |
| Molecular formula | C221H342N46O68 |
| Molecular weight | 4731.4 g/mol |
| CAS number | 2381089-83-2 |
| Form | Lyophilized powder |
| Purity | 99% Pure |
| Storage | Store lyophilized powder at -20°C. Once reconstituted, refrigerate at 2-8°C and use within the timeframe indicated by your lab protocol. |
| Intended use | Laboratory research only |
This product is sold exclusively for laboratory research use by qualified professionals and institutions. It is not a drug, food, cosmetic, or dietary supplement, and is not approved for use in humans or animals. Handling must be performed only by trained personnel in a controlled research setting.
Research overview
Retatrutide is a single peptide that activates three receptors: the glucagon receptor, the GLP-1 receptor, and the GIP receptor. In cells expressing each human receptor it drives cAMP accumulation, and a C20 fatty diacid side chain extends its circulation time. It is studied as a tool for comparing combined incretin and glucagon receptor signaling in cell-based assays.
Listed as R-3; the compound is retatrutide (LY3437943).
Research areas
- Glucagon, GLP-1, and GIP receptor signaling
- cAMP signaling assays
- Multi-receptor agonist design
Sources
Handling and storage
Store lyophilized powder at -20°C. Once reconstituted, refrigerate at 2-8°C and use within the timeframe indicated by your lab protocol.