TB500 Thymosin Beta-4
Research Compound
$42
| Pack size | 1 vial, size selected above |
| Form | Lyophilized powder |
| Purity | 99% Pure |
| Storage | Store lyophilized powder at -20°C. Once reconstituted, refrigerate at 2-8°C and use within the timeframe indicated by your lab protocol. |
| Intended use | Laboratory research only |
This product is sold exclusively for laboratory research use by qualified professionals and institutions. It is not a drug, food, cosmetic, or dietary supplement, and is not approved for use in humans or animals. Handling must be performed only by trained personnel in a controlled research setting.
Research overview
TB-500
TB-500 is a synthetic, N-acetylated heptapeptide matching residues 17–23 of thymosin β4, the actin-binding region of that protein. In laboratory studies it inhibited the proliferation and migration of stimulated hepatic stellate cells, and topical application shortened wound-closure times in mice. It has not undergone human trials, and the World Anti-Doping Agency prohibits it.
| Also known as | Thymosin β4 fragment 17–23 |
| Compound type | Synthetic heptapeptide (N-acetylated) |
| Sequence | Ac-LKKTETQ-OH |
| Molecular formula | C38H68N10O14 |
| Molecular weight | 889.0 g/mol |
| CAS number | 885340-08-9 |
Thymosin β4
Thymosin β4 is a naturally occurring 43-amino-acid peptide and a major actin-sequestering protein. TB-500 corresponds to its residues 17–23.
| Also known as | Tβ4 |
| Compound type | 43-amino-acid peptide (N-acetylated) |
| Sequence | Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES-OH |
| Molecular formula | C212H350N56O78S |
| Molecular weight | 4963.5 g/mol |
| CAS number | 77591-33-4 |
Research areas
- Actin dynamics and cell migration
- Wound-healing models
- Thymosin β4 structure–function
- Actin sequestration
- Cell migration
Sources
Handling and storage
Store lyophilized powder at -20°C. Once reconstituted, refrigerate at 2-8°C and use within the timeframe indicated by your lab protocol.